• Quality of life - Health - Food

Tumour Immunology and anti-cancer immunotherapy unit

Research unit

Description

The laboratory of cancer immunology and immunotherapy against cancer has 2 major research themes. The first is the immunology of tumors and immunotherapy against cancer and the second is the role of mRNA translation in the antigen presentation. These topics include studies on the intestinal microbiota and tumors inflammation, immunotherapy customized by monoclonal antibodies or on the cross-presentation to MHC class I on antigenic peptides. This research focuses on a better understanding of immunology in cancer patients and to improve personalized treatments to better fight this disease. This work in partnership with numerous industrial partners has already enabled the implementation of 6 patents.

Contacts

  • Mrs Laurence ZITVOGEL

https://www.gustaveroussy.fr/fr/content/umr-1015-0

Innovation themes

Map and access

114, rue Edouard Vaillant
94800 VILLEJUIF

Our research areas

Expertises

- Intestinal microbiota and inflammation / immunity, pro- or anti-tumor
-immunotherapy customized by monoclonal antibodies according to tumoral microenvieonnement
- characterization of NK infiltrating tumors
- role of antigenic peptides (MHC I)
- role of proteasome regulators (MHC I antigenic peptides)

Applications sectors

  • Biotechnology

Total number of employees

Total number of employees : 32
Number of researchers : 4
Number of doctoral students : 6

Keywords

Our results

Ecosystem

Establishments of affiliation

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Thematics

Current thematics

  • Quality of life - Health - Food
    • Therapeutic technologies (drugs, genetics, biomarkers, biomolecules, etc.)
Title

Current content

Tumour Immunology and anti-cancer immunotherapy unit
Type

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Research unit
Workforce

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Effectif total : 32
Nombre de chercheurs : 4
Nombre de doctorants : 6
Description

Current content

The laboratory of cancer immunology and immunotherapy against cancer has 2 major research themes. The first is the immunology of tumors and immunotherapy against cancer and the second is the role of mRNA translation in the antigen presentation. These topics include studies on the intestinal microbiota and tumors inflammation, immunotherapy customized by monoclonal antibodies or on the cross-presentation to MHC class I on antigenic peptides. This research focuses on a better understanding of immunology in cancer patients and to improve personalized treatments to better fight this disease. This work in partnership with numerous industrial partners has already enabled the implementation of 6 patents.
Contact informations
Contact

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Contact name Email phone number
Laurence-ZITVOGEL laurence.zitvogel@gustaveroussy.fr
URL

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https://www.gustaveroussy.fr/fr/content/umr-1015-0

Address

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114, rue Edouard Vaillant

94800 VILLEJUIF
Lab of attachment

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Keywords

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mRNAs, translation, pioneering translational products (PTPs), MHC class I, antigenic presentation, immune response of tumors, immunotherapy, intestinal microbiota, inflammation, monoclonal antibodies, immunomodulators, tests, NK, differentiation, clinical trials, antigenic peptides, nuclear ribosomes
Our search domains
Expertises

Current content

- Intestinal microbiota and inflammation / immunity, pro- or anti-tumor
-immunotherapy customized by monoclonal antibodies according to tumoral microenvieonnement
- characterization of NK infiltrating tumors
- role of antigenic peptides (MHC I)
- role of proteasome regulators (MHC I antigenic peptides)
Applications sectors

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Biotechnology

Equipments

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Our results
Valuation offer

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Examples of work

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Publications

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Scientific collaborations

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Ecosystem
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PIA links

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Carnot Institutes

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Doctoral school

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Personal informations
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