• Complex systems and software engineering
  • Digital
  • Energy, Ecology, Environment
  • Quality of life - Health - Food

Mathématiques et Informatique Appliquées du Génome à l'Environnement

Research unit


MaIAGE is made up of mathematicians, computer scientists, biocomputational scientists and biologists working together in the fields from biology and agro-environment friendly solutions, from the molecular scale to the study of individual beings, populations of ecosystems. MaIAGE develops mathematical and computational methods in order to overcome specific biological issues. It also has a hand in creating databases and software allowing biologists to use tools in the right conditions, or even exploit scientific litterature automatically.

Statistical inference and dynamic modelling are some of the unit's highest expertises, to which biocomputation, automation and algorythmics can be added. The research and engineering activities are also highly intertwined with the avenues they are aimed at, such as sustainable development, molecular biology and the biology of systems.


  • Mrs Béatrice LAROCHE

Innovation themes

Map and access

Domaine de Vilvert

Our research areas


- biocomputation and statistics
- biology of systems
- dynamic and statistical models for environmental science
- capture and formalization from text

Total number of employees

Total number of employees : 70
Number of researchers : 22
Number of doctoral students : 14

Equipment(s) open to collaboration

Academics and industry:
Biocomputation platform MIGALE: http://migale.jouy.inra.fr/


Our results

Valuation offer

- Alvis AE: online annotation editor allowing the visualisation and annotation of entities and relations in text
- CaliFloPP: calculation software for particle flow between polygon pairs
- FILTREX: Matlab software for identification, statistical inference and optimal time sampling of previsional microbiology models via particular filters

Web services:
- CompaGB : web application allowing the evaluation and comparison of Genomes Browsers as arrays or radar graphs
- DOMIRE : server using VAST (comparison of 3D protein structures) to define the limits of protein structural domains from their atomic coordinates s
- FROST : reconnaissance tool for protein folding from its amino-acid sequence

- FUNYBASE: database dedicated to the analysis and classification of proteins axtracted from complete fungal genomes
- MICADO: relational database dedicated to microbian genomes
- MOSAIC: relational database allowing the comparison of bacterial genomes within a species

Ontologies and Corpus:
- Ontologie WheatPhenotype: describes the traits of tender wheat (Triticum aestivum) and environmental factors that affect them
- Ontologie OntoBiotope: describes varied microorganisms' habitats
- Corpus BI: allows the extraction of complex events and biological interactions from PubMed references

Projects examples

- Quaero : collaboration program of innovation and industrial research in the field of automatic analysis and enrichment of numercial, multimedia and multilingual content
- FP7 BaSysBio : systemic biology focusing on the study of global regulation of gene transcription in a bacteria (Bacillus subtilis)
- BaSynthec : synthetic bacterial minimal genome for biotechnologies
- H2020 ITN List_maps
- ITN ProteinFactory
- H2020 OpenMinTed

Industrial and scientific relations

Scientific collaborations

INRA (Jouy, Rennes, Dijon, Montpellier, Toulouse...), INRIA (Rennes, Sophie, Saclay), Universities (Paris-Saclay, Paris 6, ...), AgroParisTech, etc.


Establishments of affiliation