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Laboratory of Genetics and Biology of the Cell

Research unit

Description

The main research themes developed at LGBC concern on the one hand the modalities and regulation of cell death processes, in particular at the mitochondrial level, and on the other hand, the compensatory mechanisms involved in the maintenance of tissue homeostasis at following stress involving the mitochondria or endoplasmic reticulum. For this, we use cellular models of mammals and Drosophila.

At the same time, we are carrying out collaborative projects which notably use models mimicking pathologies in Drosophila.

Contacts

  • Mrs Isabelle GUÉNAL

http://www.lgbc.uvsq.fr/

Innovation themes

Map and access

2, avenue de la source de la Bièvre
78180 MONTIGNY-LE-BRETONNEUX

Our research areas

Expertises

- mitochondria role in cell death processes
- mitochondrial dynamics
- genotoxic stress response
- oxidative and endoplasmic reticulum stress response
- apoptosis regulation by growth factors
- drosophila
- protein agregation and cell fate

Applications sectors

  • Biotechnology
  • Health / wellness
  • Cosmetics

Total number of employees

Total number of employees : 19
Number of researchers : 10
Number of doctoral students : 4

Equipment(s) open to collaboration

Academics and industry:
Facilities of the research center platform

Keywords

Our results

Valuation offer

Characterisation of cell death and survival processes
Stress response analyses (in particular genotoxic, oxidative and endoplasmic reticulum stresses)

Projects examples

http://www.lgbc.uvsq.fr/

Industrial and scientific relations

Scientific collaborations

INSERM U1173
CNRS FR3636
INSERM U892

Private collaborations

Ecosystem

Establishments of affiliation

Département(s) de recherche

  • SDV (Life sciences)