• Quality of life - Health - Food

Laboratory of Genetics and Biology of the Cell

Research unit

Description

The main research themes developed at LGBC concern on the one hand the modalities and regulation of cell death processes, in particular at the mitochondrial level, and on the other hand, the compensatory mechanisms involved in the maintenance of tissue homeostasis at following stress involving the mitochondria or endoplasmic reticulum. For this, we use cellular models of mammals and Drosophila.

At the same time, we are carrying out collaborative projects which notably use models mimicking pathologies in Drosophila.

Contacts

  • Mrs Isabelle GUÉNAL

http://www.lgbc.uvsq.fr/

Innovation themes

Map and access

2, avenue de la source de la Bièvre
78180 MONTIGNY-LE-BRETONNEUX

Our research areas

Expertises

- mitochondria role in cell death processes
- mitochondrial dynamics
- genotoxic stress response
- oxidative and endoplasmic reticulum stress response
- apoptosis regulation by growth factors
- drosophila
- protein agregation and cell fate

Applications sectors

  • Biotechnology
  • Health / wellness
  • Cosmetics

Total number of employees

Total number of employees : 19
Number of researchers : 10
Number of doctoral students : 4

Equipment(s) open to collaboration

Academics and industry:
Facilities of the research center platform

Keywords

Our results

Valuation offer

Characterisation of cell death and survival processes
Stress response analyses (in particular genotoxic, oxidative and endoplasmic reticulum stresses)

Projects examples

http://www.lgbc.uvsq.fr/

Industrial and scientific relations

Scientific collaborations

INSERM U1173
CNRS FR3636
INSERM U892

Private collaborations

Ecosystem

Establishments of affiliation

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Thematics

Current thematics

  • Quality of life - Health - Food
    • Therapeutic technologies (drugs, genetics, biomarkers, biomolecules, etc.)
Title

Current content

Laboratory of Genetics and Biology of the Cell
Type

Current content

Research unit
Workforce

Current content

Effectif total : 19
Nombre de chercheurs : 10
Nombre de doctorants : 4
Description

Current content

The main research themes developed at LGBC concern on the one hand the modalities and regulation of cell death processes, in particular at the mitochondrial level, and on the other hand, the compensatory mechanisms involved in the maintenance of tissue homeostasis at following stress involving the mitochondria or endoplasmic reticulum. For this, we use cellular models of mammals and Drosophila. At the same time, we are carrying out collaborative projects which notably use models mimicking pathologies in Drosophila.
Contact informations
Contact

Current content

Contact name Email phone number
Isabelle-GUÉNAL isabelle.guenal@uvsq.fr
URL

Current content

http://www.lgbc.uvsq.fr/

Address

Current content

2, avenue de la source de la Bièvre

78180 MONTIGNY-LE-BRETONNEUX
Lab of attachment

Current content

Keywords

Current content

Apoptosis, mitochondria, endoplasmic reticulum, p53, FGF1, Drp1, Bcl-2, Bax, VDAC, mammalian cell lines, Rb,stress response, oxidative stress, tissue homeostasis, caspase, Drosophila, presenilin, JNK pathway
Our search domains
Expertises

Current content

- mitochondria role in cell death processes
- mitochondrial dynamics
- genotoxic stress response
- oxidative and endoplasmic reticulum stress response
- apoptosis regulation by growth factors
- drosophila
- protein agregation and cell fate
Applications sectors

Current content

Biotechnology

Cosmetics

Health / Wellness

Equipments

Current content

Academics and industry: Facilities of the research center platform
Our results
Valuation offer

Current content

Characterisation of cell death and survival processes Stress response analyses (in particular genotoxic, oxidative and endoplasmic reticulum stresses)
Offers types

Current content

Examples of work

Current content

http://www.lgbc.uvsq.fr/
Publications

Current content

Scientific collaborations

Current content

INSERM U1173
CNRS FR3636
INSERM U892
Private collaborations

Current content

Ecosystem
Affiliated institutions

Current content

Institutional groups

Current content

Research departments

Current content

PIA links

Current content

Competitivness clusters

Current content

Carnot Institutes

Current content

Doctoral school

Current content

Personal informations
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