Laboratoire Matériaux et Santé (MS)

Research unit

Description

The MS lab is a research unit from Université Paris Sud which mainly focuses on the aging of pharmaceutical materials and drugs. It does so via 2 main research axis: (i) plastic materials used in pharmaceutical products and medical devices, and (ii) the drug modifications during pharmaceutical and environmental processes. The methodology for material aging study is based on a bulk and surface analysis of the material linked to the study of the interactions with biological media. This method allows the definition of the complex and dynamic relationships of the material with its environment (biological fluids, pharmaceutical formulations..) depending on the aging conditions. The drug stability studies are mainly conducted by liquid chromatography/mass spectrometry MS has major industrial and economic partnerships for and research.

Contacts

  • Mrs Najet YAGOUBI

http://www.materiauxetsante.u-psud.fr/

Map and access

17 Avenue des Sciences
Faculté de Pharmacie
91400 ORSAY

Our research areas

Expertises

- low weight molecular compound diffusion, blooming and migration through medical grade polymer and their impact on biocompatibility and material biostability
- scientific and preclinical rational
- drug physical/chemical characteristics and stability

Applications sectors

  • Biotechnology
  • Health / wellness
  • Chemistry / Plastics (Glue, Plastic, Rubber...)
  • Materials (Metal, Glass, Ceramic, Composite...)

Total number of employees

Total number of employees : 11
Number of researchers : 5
Number of doctoral students : 2

Equipment(s) open to collaboration

- atomic force microscopy and scanning electron microscopy- goniometer
- gas chromatography
- mass spectrometry- technical platform for liquid chromatograpy (HPLC, SEC)
- UV weathering tester
- Technical platform in thermal analysis (DSC, ATG)
- Cell culture for determination of the biocompatibility

Keywords

Our results

Valuation offer

-Surface analysis
-Extractible and leachable analysis
-In vitro biocompatibility studies

Industrial and scientific relations

Scientific collaborations

- Institut Lavoisier de Versailles (Université de Versailles Saint Quentin en Yvelines), Institut des Sciences Moléculaires d'Orsay (Université Paris Sud), INRA-AgroParisTech, Laboratoire de Chimie Physique (Université Paris Sud), Institut de Chimie Radicalaire (Université Aix-Marseille), Laboratoire de Biomatériaux Pour la Santé (Université Paris XIII), Groupe Hospitalier Pitié-Salpêtrière, Hôpital Mondor, Vygon, Novomed

Private collaborations

- numerous industrial collaborations (expertise)

Ecosystem

Establishments of affiliation

Département(s) de recherche

  • SDV (Life sciences)