Laboratoire Matériaux et Santé (MS)

Research unit

Description

The MS lab is a research unit from Université Paris Sud which mainly focuses on the aging of pharmaceutical materials and drugs. It does so via 2 main research axis: (i) plastic materials used in pharmaceutical products and medical devices, and (ii) the drug modifications during pharmaceutical and environmental processes. The methodology for material aging study is based on a bulk and surface analysis of the material linked to the study of the interactions with biological media. This method allows the definition of the complex and dynamic relationships of the material with its environment (biological fluids, pharmaceutical formulations..) depending on the aging conditions. The drug stability studies are mainly conducted by liquid chromatography/mass spectrometry MS has major industrial and economic partnerships for and research.

Contacts

  • Mrs Najet YAGOUBI

http://www.materiauxetsante.u-psud.fr/

Map and access

17 Avenue des Sciences
Faculté de Pharmacie
91400 ORSAY

Our research areas

Expertises

- low weight molecular compound diffusion, blooming and migration through medical grade polymer and their impact on biocompatibility and material biostability
- scientific and preclinical rational
- drug physical/chemical characteristics and stability

Applications sectors

  • Biotechnology
  • Health / wellness
  • Chemistry / Plastics (Glue, Plastic, Rubber...)
  • Materials (Metal, Glass, Ceramic, Composite...)

Total number of employees

Total number of employees : 11
Number of researchers : 5
Number of doctoral students : 2

Equipment(s) open to collaboration

- atomic force microscopy and scanning electron microscopy- goniometer
- gas chromatography
- mass spectrometry- technical platform for liquid chromatograpy (HPLC, SEC)
- UV weathering tester
- Technical platform in thermal analysis (DSC, ATG)
- Cell culture for determination of the biocompatibility

Keywords

Our results

Valuation offer

-Surface analysis
-Extractible and leachable analysis
-In vitro biocompatibility studies

Industrial and scientific relations

Scientific collaborations

- Institut Lavoisier de Versailles (Université de Versailles Saint Quentin en Yvelines), Institut des Sciences Moléculaires d'Orsay (Université Paris Sud), INRA-AgroParisTech, Laboratoire de Chimie Physique (Université Paris Sud), Institut de Chimie Radicalaire (Université Aix-Marseille), Laboratoire de Biomatériaux Pour la Santé (Université Paris XIII), Groupe Hospitalier Pitié-Salpêtrière, Hôpital Mondor, Vygon, Novomed

Private collaborations

- numerous industrial collaborations (expertise)

Ecosystem

Establishments of affiliation

Edit request

You enter the « edit request » mode. After sending your modifications, they will first be validated by the Plug in labs University Paris Saclay team, before appearing on the platform.

Thematics

Current thematics

Title

Current content

Laboratoire Matériaux et Santé (MS)
Type

Current content

Research unit
Workforce

Current content

Effectif total : 11
Nombre de chercheurs : 5
Nombre de doctorants : 2
Description

Current content

The MS lab is a research unit from Université Paris Sud which mainly focuses on the aging of pharmaceutical materials and drugs. It does so via 2 main research axis: (i) plastic materials used in pharmaceutical products and medical devices, and (ii) the drug modifications during pharmaceutical and environmental processes. The methodology for material aging study is based on a bulk and surface analysis of the material linked to the study of the interactions with biological media. This method allows the definition of the complex and dynamic relationships of the material with its environment (biological fluids, pharmaceutical formulations..) depending on the aging conditions. The drug stability studies are mainly conducted by liquid chromatography/mass spectrometry MS has major industrial and economic partnerships for and research.
Contact informations
Contact

Current content

Contact name Email phone number
Najet-YAGOUBI najet.yagoubi@universite-paris-saclay.fr
URL

Current content

http://www.materiauxetsante.u-psud.fr/

Address

Current content

17 Avenue des Sciences
Faculté de Pharmacie
91400 ORSAY
Lab of attachment

Current content

Keywords

Current content

Medical devices, polymers, leachables, biocompatibility, drug degradation
Our search domains
Expertises

Current content

- low weight molecular compound diffusion, blooming and migration through medical grade polymer and their impact on biocompatibility and material biostability
- scientific and preclinical rational
- drug physical/chemical characteristics and stability
Applications sectors

Current content

Biotechnology

Chemistry / Plastics (Glue, Plastic, Rubber...)

Health / Wellness

Materials (Metal, Glass, Ceramic, Composite...)

Equipments

Current content

- atomic force microscopy and scanning electron microscopy- goniometer - gas chromatography - mass spectrometry- technical platform for liquid chromatograpy (HPLC, SEC) - UV weathering tester - Technical platform in thermal analysis (DSC, ATG) - Cell culture for determination of the biocompatibility
Our results
Valuation offer

Current content

-Surface analysis -Extractible and leachable analysis -In vitro biocompatibility studies
Offers types

Current content

Examples of work

Current content

Publications

Current content

Scientific collaborations

Current content

- Institut Lavoisier de Versailles (Université de Versailles Saint Quentin en Yvelines), Institut des Sciences Moléculaires d'Orsay (Université Paris Sud), INRA-AgroParisTech, Laboratoire de Chimie Physique (Université Paris Sud), Institut de Chimie Radicalaire (Université Aix-Marseille), Laboratoire de Biomatériaux Pour la Santé (Université Paris XIII), Groupe Hospitalier Pitié-Salpêtrière, Hôpital Mondor, Vygon, Novomed
Private collaborations

Current content

- numerous industrial collaborations (expertise)
Ecosystem
Affiliated institutions

Current content

Institutional groups

Current content

Research departments

Current content

PIA links

Current content

Competitivness clusters

Current content

Carnot Institutes

Current content

Doctoral school

Current content

Personal informations
Back to top