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Institut Galien Paris-Saclay (IGPS)

Research unit

Description

The Institut Galien Paris Sud (IGPS) is a major international player in nanomedicine research. His goal is to develop nanotechnologies to deliver drugs to target cell populations and modulate their effects or for in vitro diagnostics and in vivo. The unit enjoys excellent international visibility thanks to its numerous publications and communications. His innovative work on nanomedicine attracts many collaborations, as evidenced by registered patents and industrial contracts. It is divided into three main poles (Physical Chemistry, Galenic Pharmaceuticals, Analytics) around which 7 teams with complementary skills are concentrated. It is a member of LabEx Lermit and NanoSaclay as well as the Paris-Sud Institute of Therapeutic Innovation (IPSIT). The IGPS has numerous scientific facilities grouped into common services for some throughout the site, which are available to everyone. They allow an optimal collaboration between the different teams of the unit and also attract external teams.

Contacts

  • Mrs Myriam TAVERNA-BONVENTO

http://www.umr-cnrs8612.u-psud.fr/index.php

Innovation themes

Map and access

17 Avenue des Sciences
Faculté de Pharmacie
91400 ORSAY

Our research areas

Expertises

- interactions between lipids, polymers, proteins, surfactants and active substances
- molecule / membrane interactions
- macromolecular chemistry
- nanovectors, nanodrugs
- nanotechnology for diagnosis
- controlled release systems
- biological barriers crossing
- nanotoxicology

Applications sectors

  • Biotechnology
  • Health / wellness
  • Education / Training
  • Chemistry / Plastics (Glue, Plastic, Rubber...)
  • Materials (Metal, Glass, Ceramic, Composite...)
  • Cosmetics

Total number of employees

Total number of employees : 146
Number of researchers : 64
Number of doctoral students : 44

Equipment(s) open to collaboration

Academics and industry:
Some of the equipment in the unit is grouped into common services Service of radioactivity handling of products at risk Rheology Service (http://www.umr-cnrs8612.u-psud.fr/plateformerheologie.php).
The unit has heavy equipment:
- 4 cell QCM-D system
- atomic force microscope
- differential scanning calorimetry
- X-ray diffractometer
- capillary electrophoresis coupled to the mass
- beta scintillation counter and BetaImager BioSpaceLab
- microfluidizer
- spray dryer
- granlometers

Keywords

Our results

Valuation offer

Expertise:
- Biomimetic membrane models
- Biological barriers models (lungs, brain, digestive tract)
- Animal models cancer, inflammation
- Artificial or reconstituted assemblages of simple or complex lipids mixtures
- Design of nanoparticles based on inorganic materials (polymers, lipids)
- Design of nanoprodrogues
- Physico-chemical and mechanical characterization of the systems: rheology, surface properties, adhesion Characterization of supramolecular architectures
- Nanotechnologies for diagnosis
- Analysis of therapeutic proteins

Patents:
- http://www.fist.fr/catalogue-cnrs/new -particulate-system-for-microencapsulation-2 /
- http://www.fist.fr/catalogue-cnrs/new-class-of-polymer-encapsulation-particles-2-2/?pdf=true
- http://www.fist.fr/catalogue-cnrs/new-galenic-formulation-for-adsorbing-undesirable-molecules-in-the-digestive-tract-2-2/?pdf=true
- http://www.fist.fr/catalogue-cnrs/new-liposome-concentration-process-governed-by-alpha-cyclodextrin-2-2/?pdf=true

Projects examples

- projects COFECUB (Brazil), PHC Tassili (Algeria), PHC Galilee (Italy), CEFIPRA (India): student exchange funding programs

Industrial and scientific relations

Scientific collaborations

- France: CNRS, INSERM, AP-HP, ANR, CentraleSupelec, ESPCI Labex LERMIT and Labex NANO Saclay
- Europe: Germany, Belgium, Denmark, Slovenia, Romania, Spain, Italy, Norway, England, Serbia
- International, USA, Jordan, Brazil, Spain, Turkey, Austria, Algeria, India, Canada, China, Colombia, Egypt, Ivory Coast, Australia, Syria, Tunisia, Vietnam, Russia, Morocco, Mexico, Lebanon

Private collaborations

The Galien Paris-Sud Institute has collaborations with Start-ups, SMEs and major French, European and international groups.

Ecosystem

Establishments of affiliation

Département(s) de recherche

  • Chemistry
  • SDV (Life sciences)

Liens PIA

  • LabEx LERMIT