• Energy, Ecology, Environment
  • Quality of life - Health - Food

I2BC / Département Microbiologie

Research team


The Microbiology Department is part of the Institute for Integrative Cell Biology (I2BC). The different groups in the department work mainly on these three themes:
- microbial metabolism
- envelope of micro-organisms
- interactions of microbes with their hosts and the environment.
Through these themes, there are many organisms that are studied (bacteria, archaea, viruses), from very diverse biotopes (soils, water, extreme environments, human microbiomes, animals, plants).
The teams are particularly involved in the development of economic and societal applications (health, environment, bioenergy).


  • Mr Jean-Luc PERNODET

Innovation themes

Lab of attachment

Map and access

Avenue de la Terrasse
Bâtiment 21

Our research areas


- molecular biology of corynebacteria and mycobacteria
- endotoxins, structures and responses of the host
- biology and biotechnologies of cyanobacteria (bio-fuels and detection of metal pollutants)
- genomics and microbial biodiversity of biofilms
- plant-bacteria interactions: ecological impact of genetically modified plants, biological control ...
- enzymology and non-ribosomal peptide biosynthesis
- bacterial envelopes and antibiotics
- cellular biology of archaea
- bacterial adaptation to environmental changes
- molecular microbiology of actinomycetes
- genetic infection, evolution of emerging pathogens
- Regulatory RNAs in Clostridia
- energetic metabolism of Streptomyces

Applications sectors

  • Biotechnology
  • Other business
  • Energy

Total number of employees

Total number of employees : 146
Number of researchers : 66

Equipment(s) open to collaboration

- I2BC platforms
- anaerobic chamber for the study of archaea
- Beads4Med platform: direct determination of the genotype of bacteria responsible for tuberculosis, salmonellosis, legionella


Our results

Valuation offer

Know-how and techniques:
- model organisms Corynebacterium glutamicum and Mycobacterium smegmatis
- data mining methods

Databases and software:
- genomic sequences of ~ 3000 prokaryotic organisms
- BAGET: sequence and immediate environment of any gene from these organisms http://archaea.u-psud.fr/Baget_help.html.
- FITBAR: prediction of regulars at the level of a complete genome http://archaea.u-psud.fr/fitbar/.
- ABSYNTE: analysis of gene conservation (synteny) of microorganisms http://archaea.u-psud.fr/absynte/.
- SYNTTAX: analysis of synteny according to the taxonomic classification of species http://archaea.u-psud.fr/synttax/.

Projects examples

- structure and composition of the mycomembrane
- plant protection by biocontrol agents
- development of new multiparametric methods for CRISPR typing and detection of antibiotic resistance mutations on optical and electrochemical micro and nanotechnology chips
- Data mining and Automated learning on CRISPR data from Mycobacterium tuberculosis and Salmonella enterica


Establishments of affiliation