Within the François Jacob Institute of Biology of the CEA, the CNRGH (National Centre for Research in Human Genomics) aims to answer scientific questions raised by research in genetics and genomics of human diseases and has a recognised expertise in genotyping and high-throughput sequencing, thanks to the development and implementation of innovative and integrated technologies. In this respect, the CNRGH operates a very high-throughput genotyping platform based on Illumina® DNA chip technology, and is one of the 3 European leaders in this field. Fully robotized, this platform allows for rapid pan-genomic studies on large numbers of samples, thanks to the use of very high density chips analysing between 200,000 and 5 million markers simultaneously. Optimal traceability is ensured thanks to the tracking of all samples by a barcode system and the piloting of the platform by means of a LIMS (Laboratory Information Management System) tracing all the stages of the genotyping process. The current throughput is 1200 DNA samples per week, corresponding to the production of more than 2,000,000,000 genotypes on average per week.
2, rue Gaston Crémieux
CEA Paris-Saclay, site d'Evry, CNRGH