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Quality of life - Health - Food
Physiopathogenesis and treatment of liver diseases
Research unit
The goal of the Physiopathogenesis and Treatment of Liver Diseases Unit is to develop translational research in hepatic pathologies on two major themes: hepatic cancers on the one hand and hepatitis (including viral) on the other hand with the will to propose innovative therapies. It is made up of renowned researchers and clinicians as well as ATRs who make the bridge between the laboratory and the patient's bed. The unit is very involved in international clinical trials for the management of hepatic carcinomas and hepatitis. Furthermore, it benefits from the equipment provided by the Lwoff Institute technical platform and the Hepatinov DHU experts network.
Innovation themes
12-14, av. Paul Vaillant Couturier
Centre Hépato-Biliaire, Hôpital Paul Brousse
94800 VILLEJUIF
Expertises
- management of liver diseases (including carcinomas)
- transplantation, transplant rejection, immunity
- liver cancer
- acute and chronic hepatitis, steatosis
- cytoskeletal dynamics
- mitochondrial regulation, autophagy
- viruses associated with hepatitis and carcinomas (HBV, HCV ...)
Applications sectors
- Biotechnology
- Health / wellness
Total number of employees
Number of researchers : 41
Number of doctoral students : 10
Keywords
Projects examples
- MODHEP project (FP7): Systems biology of liver cancer, an integrative genomic-epigenomic approach http://www.modhep.eu/
- Inserm U1110: HRas induces HCV penetration in hepatocytes by targeting the tetraspanine receptor (Cell Host and Microbe 2013)
Industrial and scientific relations
Scientific collaborations
- France: Inserm, ENS Cachan, CEA, INRA - Europe: Spain, England
- International: China, Lebanon
Establishments of affiliation
