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Quality of life - Health - Food
Modèles de cellules souches malignes et thérapeutiques
Research unit
The team brings together 3 independent research units to generate synergistic interactions in the field of malignant and therapeutic stem cells. In this configuration, Unit 935 associates a team with expertise in adult and embryonic stem cell biology with two teams working on membrane compartmentalization and chronobiology / chronotherapy. This association is expected to open new fields of research on development and differentiation and promote technology transfer. These teams are in close contact with a 4th team coordinating a national transfer technology network called INGESTEM dedicated to strategies for reprogramming adult cells into induced pluripotent stem cells (iPS).
Innovation themes
7, rue Guy Moquet
Campus du CNRS, Bâtiment A
94800 VILLEJUIF
Expertises
-leukemia and cancer
-differenciation of cells
Applications sectors
- Health / wellness
Total number of employees
Number of researchers : 53
Number of doctoral students : 9
Keywords
Projects examples
-stem cells of chronic myeloid leukemia
-modeling of tumor stem cells using iPSC - BRCA1 Positive Hereditary Cancer Model
-application in regenerative medicine of iPSC
Membrane compartmentation and cell differentiation:
-regulation of Nnotch signaling by Tspan C8 tetraspanins
-decode the mechanisms of muscle cell fusion by studying tetraspanins.
Chronotherapy of liver cancers:
-chronoprevention of cancer
-personalized chronotherapy of cancer