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Modèles de cellules souches malignes et thérapeutiques

Research unit


The team brings together 3 independent research units to generate synergistic interactions in the field of malignant and therapeutic stem cells. In this configuration, Unit 935 associates a team with expertise in adult and embryonic stem cell biology with two teams working on membrane compartmentalization and chronobiology / chronotherapy. This association is expected to open new fields of research on development and differentiation and promote technology transfer. These teams are in close contact with a 4th team coordinating a national transfer technology network called INGESTEM dedicated to strategies for reprogramming adult cells into induced pluripotent stem cells (iPS).


Innovation themes

Map and access

7, rue Guy Moquet
Campus du CNRS, Bâtiment A

Our research areas


-leukemia and cancer
-differenciation of cells

Applications sectors

  • Health / wellness

Total number of employees

Total number of employees : 63
Number of researchers : 53
Number of doctoral students : 9


Our results

Projects examples

leukemia, cancer and pluripotency induced:
-stem cells of chronic myeloid leukemia
-modeling of tumor stem cells using iPSC - BRCA1 Positive Hereditary Cancer Model
-application in regenerative medicine of iPSC

Membrane compartmentation and cell differentiation:
-regulation of Nnotch signaling by Tspan C8 tetraspanins
-decode the mechanisms of muscle cell fusion by studying tetraspanins.

Chronotherapy of liver cancers:
-chronoprevention of cancer
-personalized chronotherapy of cancer


Establishments of affiliation