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Quality of life - Health - Food
Inflammation, chemokines and immunopathology
Research unit
The Inflammation, Chimiokines and Immunopathology laboratory is interested in the pathophysiological mechanisms of the immune system and inflammation.Three teams are thematically sharing the work and are interested respectively in the immunological deregulation at the origin of the viral resistances , the influence of the intestinal microbiota on the liver resident macrophages, and finally the autoimmunities / immunodeficiencies. The presence of clinicians in the unit allows a translational approach research, as well as its membership in IPSIT and LabEx LERMIT leads to therapeutic innovations.
Innovation themes
32, rue des Carnets
92140 CLAMART
Expertises
- host / virus interference, microbiota
- immunotoxicology and allergy
- hepatic pathophysiology (obesity, alcoholic disease)
- autoimmunity and immunodeficiencies
- anti-tumor immunity
- therapeutic Innovation
Applications sectors
- Biotechnology
- Health / wellness
- Education / Training
- Chemistry / Plastics (Glue, Plastic, Rubber...)
- Materials (Metal, Glass, Ceramic, Composite...)
- Cosmetics
Total number of employees
Number of researchers : 26
Number of doctoral students : 18
Equipment(s) open to collaboration
- IPSIT Platform
Keywords
- autoimmunity
- immunodeficiency
- human papillomavirus
- hemotopoietic stem cells
- chemokine
- cellular migration
- plasmocyte
- dendritic cell
- lymphocyte
- keratinocyte
- mouse model
- keratinocyte 3D culture
- mass cytometry
- translational research
- neutrophyl
- netose
- contact allergy
- NRF2
- biotherapy
- T-repertoire
- intestinal microbiota
- steatosis and liver cancer
- macrophage
- kurpfer cell
- bile acid
- inflammatory cytokines
- clinical trial
Projects examples
- ONCORNET
- inserm microbiote
- Guidelines in toxicology / anti-allergic therapies and vaccination
Industrial and scientific relations
Private collaborations
- collaboration with several major companies