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I2BC / Département Virologie

Research team

Description

The Virology Department is part of the Institute of Integrative Cell Biology (I2BC) and focuses its research on two main themes, the host-virus interaction and the determination of the atomic structure of macromolecular assemblages formed during an infection. viral.
More transversal themes also emerge from the department's activities:
- mechanism of the viral entry
- viral assembly and transport and intracellular transport of viral and subviral particles
- innate immunity.
This research is fundamental to identify new targets and put in place new therapeutic strategies against viral diseases

Contacts

Innovation themes

Lab of attachment

Map and access

Avenue de la Terrasse
Bâtiment 21
91190 GIF-SUR-YVETTE

Our research areas

Expertises

- Escherichia coli infection process by bacteriophage T5
- assembly of caudal bacteriophages and infection of Gram-positive bacteria by these viruses
- correlative structural virology by electronic cryomicroscopy and radiocristallography
- rhabdovirus
- Molecular biology of rotavirus
- virulence and latency of herpesviruses

Applications sectors

  • Other business
  • Health / wellness

Total number of employees

Total number of employees : 45
Number of researchers : 26

Equipment(s) open to collaboration

I2BC plateform

Keywords

Our results

Valuation offer

- mouse model mimicking HSV-1 infection
- fluorescent viruses and live-cell imaging
- reverse genetics technique
- cryo-electron microscopy and radiocristallography

Ecosystem

Establishments of affiliation