• Quality of life - Health - Food

Genetic Stability and Oncogenesis

Research unit

Description

The Laboratory Genetic Stability and Oncogenesis works on the cellular and molecular response to DNA alteration. These alterations may be responsible for developmental abnormalities, premature aging, predisposition for the onset of cancer or cell death. The research therefore focuses on understanding the repair mechanisms of human and murine cellular DNA from biochemical, genetic, molecular and cellular analyzes. This work has already led to the creation of numerous innovations protected by 4 patents.

Contacts

  • Mrs Patricia-Laila KANNOUCHE

https://www.gustaveroussy.fr/fr/content/umr-8200-1

Innovation themes

Map and access

114, rue Edouard Vaillant
94805 VILLEJUIF

Our research areas

Expertises

- role of polymerases in cancer
- recombination, repair and DNA integrity
- signal pathways FANC / BRCA
- cell division and genome stability
- replication stress, genetic instability and mitosis

Applications sectors

  • Biotechnology
  • Health / wellness

Total number of employees

Total number of employees : 77
Number of researchers : 18
Number of doctoral students : 16

Keywords

Our results

Ecosystem

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Thematics

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  • Quality of life - Health - Food
    • Therapeutic technologies (drugs, genetics, biomarkers, biomolecules, etc.)
Title

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Genetic Stability and Oncogenesis
Type

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Research unit
Workforce

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Effectif total : 77
Nombre de chercheurs : 18
Nombre de doctorants : 16
Description

Current content

The Laboratory Genetic Stability and Oncogenesis works on the cellular and molecular response to DNA alteration. These alterations may be responsible for developmental abnormalities, premature aging, predisposition for the onset of cancer or cell death. The research therefore focuses on understanding the repair mechanisms of human and murine cellular DNA from biochemical, genetic, molecular and cellular analyzes. This work has already led to the creation of numerous innovations protected by 4 patents.
Contact informations
Contact

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Contact name Email phone number
Patricia-Laila-KANNOUCHE patricia.kannouche@gustaveroussy.fr
URL

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https://www.gustaveroussy.fr/fr/content/umr-8200-1

Address

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114, rue Edouard Vaillant

94805 VILLEJUIF
Lab of attachment

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Keywords

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Genome instability, DNA repair, DNA replication, PARP, cellular divisions, biosensor, oxydative stress, recombination, mitosis, chromosomic segregation, mutational landscape, immune response, immuno-therapy, skin cancer, thyroid cancer, kidney cancer, MSI tumor, lymphomas, anemia of Fanconi
Our search domains
Expertises

Current content

- role of polymerases in cancer
- recombination, repair and DNA integrity
- signal pathways FANC / BRCA
- cell division and genome stability
- replication stress, genetic instability and mitosis
Applications sectors

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Biotechnology

Health / Wellness

Equipments

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Our results
Valuation offer

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Examples of work

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Publications

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Scientific collaborations

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Private collaborations

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Ecosystem
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Carnot Institutes

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Doctoral school

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