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Genetic Stability and Oncogenesis

Research unit


The Laboratory Genetic Stability and Oncogenesis works on the cellular and molecular response to DNA alteration. These alterations may be responsible for developmental abnormalities, premature aging, predisposition for the onset of cancer or cell death. The research therefore focuses on understanding the repair mechanisms of human and murine cellular DNA from biochemical, genetic, molecular and cellular analyzes. This work has already led to the creation of numerous innovations protected by 4 patents.


  • Mrs Patricia-Laila KANNOUCHE

Innovation themes

Map and access

114, rue Edouard Vaillant

Our research areas


- role of polymerases in cancer
- recombination, repair and DNA integrity
- signal pathways FANC / BRCA
- cell division and genome stability
- replication stress, genetic instability and mitosis

Applications sectors

  • Biotechnology
  • Health / wellness

Total number of employees

Total number of employees : 77
Number of researchers : 18
Number of doctoral students : 16


Our results


Establishments of affiliation