• Complex systems and software engineering
  • Digital
  • Energy, Ecology, Environment
  • Mobility and transport
  • Quality of life - Health - Food
  • Social - Societal - Solidarity Innovation

Computer Science, Bioinformatics and Complex Systems (IBISC)

Research unit


The research carried out at IBISC focuses on simulation, conception, and validation of complex systems (both living and artificial). IBISC is made up of 4 teams (AROBAS, COSMO, IRA2, SIMOB) studying 2 main themes : STIC & Vivant (computational biology, biomedical image treatment, individual assistance ...) and STIC & Smart System (autonomous systems, open and safe systems ...). IBISC owns several platforms referenced and supported by Génopole : EVR@ (virtual environments and augmented reality -http://evra.ibisc.univ-evry.fr/-) and EvryRNA (http://evryrna.ibisc.univ-evry.fr/), but also varied platforms focused on smart systems (2 wheeled vehicles, drones, robots).



Innovation themes

Map and access

23, boulevard de France
91034 EVRY

Our research areas


- algorithmics and operational research
- formal methods and multiagent systems
- RNA bioinformatics
- statistical learning
- dynamic systems
- human machine interaction
- augmented and virtual reality
- ambiant robotics
- smart systems
- complex systems modelling
- image treatment

Applications sectors

  • IT / software
  • Aeronautics / Aerospace
  • Automotive industry
  • Transportation / Logistics
  • Agri-food industry
  • Biotechnology
  • Personal services / services to individuals

Total number of employees

Total number of employees : 125
Number of researchers : 55
Number of doctoral students : 55

Equipment(s) open to collaboration

Academics and industry:
- The EvryRNA platform (http://evryrna.ibisc.univ-evry.fr) is a web server providing various algorithms and bioinformatics tools developed in the laboratory IBISC of UEVE/Genopole, and dedicated to the prediction and the analysis of non-coding RNAs (ncRNAs). These RNAs are regulators of gene expression control and genome stability. They are involved in different biological processes, and some of them, including microRNAs, are known to be involved in many diseases such as cancer and neurodegenerative diseases. Their study provides insight into how living organisms function, including differentiation and cell proliferation, but also to consider new therapeutic approaches for genetic diseases and cancer.
- The ISThMe platform (Illustration de Stratégies de prescription Médicale - medical strategies and prescriptions)
- The EVR@ platform (Environnements Virtuels et de Réalité Augmentée) is made up of 5 sub-platforms :
1- EVR@-IM: immersive platform : 4 active stereoscopic projection planes 2,5mX2mX2m, real time head and hand tracking, two 3D haptic feedback systems -PHANTOM OVNI-
2- EVR@-HS: semi-immersive platform : 3,2mX2,4m screen and active stereoscopic projector, real time head and hand tracking
3- EVR@-TR: mobile VR platforms : multitouch tactile table with active sterescopy,real time head and hand tracking, 3D haptic feedback systems -PHANTOM OVNI- , Oculus Rift VR headset, Kinect camera and LeapMotion sensor
4- EVR@-WE: AR equipment, VR headset (nVisor-ST), cameras, GPS sensors, accelerometers
5- EVR@-RO: robotic devices that can be controlled online, including 2 robotic arms (FANUC LRMate 200i), 2 humanoid robots (NAO), 2 mobile robots
- Flying zone for drones
- 2 wheeled vehicles designed for passive and active safety


Our results

Valuation offer

- Méthodes et appareil de configurations de signaux. F. d'Alché-Buc , D. Zwierski, J.-P. Nadal.
- Système de contrôle de la phase de décharge des cycles de charge-décharge d'une batterie rechargeable, et d'un dispositif hôte muni d'une batterie intelligente. J.-N. Patillon, F. d'Alché-Buc, J.-P. Nadal.
- Method of drilling a ground using a robobtic arm (Laredj Benchikh, Daniel Perpezat, Lotfi Beji, Sara Cascarino : France, Patent n° : WO 2016005701 A2, 2016 - System and Method for the Synchronous Reproduction of Movements of Hand or End Member by a Robot. Laredj Benchikh, France, Patent n° : WO 2011/039429 A1. 2011.
- Method for Training a Robot or the Like, and Device for Implementing Said Method. Laredj Benchikh, France, Patent n° : WO 2009/090542 A2. 2009.
- Optimisation du processus d'assemblage des interrupteurs de haute tension. Wu, F. Chu (Peng) et al, n° CN102930073 A, Chine, 2013.

- bioinformatics: OKVAR-Boost software and plateforme EvryRNA (Tfold, P-DCFold, SSCA, miRNAFold, miRBoost, ncRNAclassifier, piRPred, IpiRId, BioKop, miRBoost-Plant)
- machine learning : OPERA-lib
- AR : ARCS (Framework RA http://arcs.ibisc.univ-evry.fr)
- Others : nsgp R package

Projects examples

- Edrone (Europe : 2017-2020): Educational for Drones (Drone architecture, piloting techniques, drones equipment for measurement and monitoring activities, processing of measurement data, drones maintenance, Laws for the privacy, risk analysis and prevention,...)
- CESAAR-AVC(CIFRE 2017-2020 ): Conception and evaluation of a support system for self-rehabilitation of upper limb with virtual reality after CVA.
- VIROLO++ ( ANR 2016-2019) : study of motorbike turning: applications to training and ITS.
- Quasicool (ANR JCJC 2013-2017) : cooling of quasicrystals: from random to periodic tesselations.
- NewTun ( FUI 2012-2017): new tunnel building methods (ground movements interactive checking, pre-retaining structure sizing, pre-retaining structure automation, instrumentation).
- SIRAM (CIFRE 2012-2016) : To a mobile virtual reality interactive system for supervision of industrial maintenance scenarios.
- algorithm and fast software for the search of potential microRNAs in genome sequences (software available on the EvryRNA pplatform and used by the international scientific community).

Industrial and scientific relations

Scientific collaborations

- France: Institut français des sciences et technologies des transports, de l'aménagement et des réseaux (IFSTTAR), Institut des plantes de Paris-Saclay Saclay, Institut Curie, laboratories: LIMSI, ENS-SATIE, LIP6, L2S, LISV, ISSB (Institut de Biologie Synthétique et des Systèmes (Evry), CHSF and Visiome group, IRBA -
- International : several Hubert Curien partnerships (Orchid with Taïwan, Polonium with la Pologne) BFHZ with Univ. Regensburg, Cathedra Francesa with escola de Medicina de Sao Paolo (Brésil), Centre de Developpement des Technologies Avancées (CDTA d'Alger, ALgérie), Tongji University, Fuzhou University, Xi'an Jiaotong University, University of Sicene and Technology of China, Northwestern Polytechnic University, Nanging Agricutural University, MLR MIT CAmbridge, Automated Vehicles, VSS Lab, Mexico, Université de Constantine 1 et de Constantine 2 (Algérie), Institut Suisse de Bioinformatique (SIB)

European projects:
- ecoDriver (2011-2015)
- eFuture (2010-2013) - Edrone Educational for Drone (2016-2019)
FUI project : NewTun (2012-2017) ANR projects:
- VIROLO++ (2016-2019)
- Quasicool (2013-2017)
- SVeDaS (JCJC 2017-2020)
- OATA (JCJC 2016-2019)
- COOPERCOM (2011-2014)
- ABV (2009-2013)
- ORIGAMI (2010-2013)

Private collaborations

- collaboration with many companies


Establishments of affiliation