• Quality of life - Health - Food

Chimie et modélisation pour la biologie du cancer (CMBC)

Research unit


The central activity of the CMIB unit is to develop small molecules to investigate and control the biological activities of the main targets involved in cancer. These are essentially non-B (quadruplex) nucleic acid structures and kinases. IR-photoexcitable probes designed for both subcellular monitoring and targeted photo-aging are also important research axes. The drug and probe design activity is supported by the molecular modeling approach and Multimodal imaging (TEM, NanoSIMS, MRI). These approaches include the development of image processing and analysis methods as well as the design of software tools and protocols for biology imaging. The CMIB unit hosts the Institut Curie-CNRS library, 9000 chemical compounds, preclinical MRI imaging and chemical imaging platforms.


  • Mrs Florence MAHUTEAU-BETZER

Innovation themes

Map and access

UMR9187/U1196, Institut Curie - Centre Universitaire, Bâtiment 110-112
91405 ORSAY

Our research areas


- G-quadruplex targeting agents
- DNA targeted fluorescent dyes
- kinase inhibitors
- photo and radiosensitizers for retinoblastoma and glioblastoma therapy
- medicinal chemistry (to optimize, building targeted libraries)
- molecular dynamics and virtual screening
- 2D and 3D multimodal imaging for chemical mapping
- development of software and acquisition processing and analysis of images

Applications sectors

  • IT / software
  • Biotechnology
  • Other business
  • Health / wellness
  • Chemistry / Plastics (Glue, Plastic, Rubber...)

Total number of employees

Total number of employees : 54
Number of researchers : 18
Number of doctoral students : 7


Our results

Projects examples

Industrial and scientific relations

Private collaborations

Startup ABIVAX


Establishments of affiliation