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Quality of life - Health - Food
Biologie du Développement et Reproduction (BDR)
Research unit
UMR BDR research focuses on the mechanisms of phenotype development in farmed mammals.
The objective is to study the impact during embryonic and fetal development, culture medium, maternal nutrition, environmental pollutants, and livestock systems, on growth, health and the fertility of the offspring.
This work combines observations and measurements on cells, embryos, fetuses and animals at different ages. They aim at an understanding of the mechanisms involved, by imaging or molecular (epigenetic, metabolic and transcriptomic) analyzes. Research is carried out simultaneously on several species (mouse, rabbit, ruminants) allowing a comparative physiology approach. This work also uses reproductive biotechnologies used in animal husbandry.
Innovation themes
INRA - Domaine de Vilvert - Bâtiment 230
78352 JOUY-EN-JOSAS
Expertises
- developmental biology
- maternal-fetal interactions-placenta
- ovarian and testicular differentiation
-gametes formation
- epigenetics
- endocrinology
- pluripotency-stem cells
- genomes edition and epigenomas
Applications sectors
- Biotechnology
- Health / wellness
Total number of employees
Number of researchers : 26
Number of doctoral students : 11
Equipment(s) open to collaboration
Imaging platform (confocal and whole animal) MIMA2-BDR
- genetic modifications workshop in mammals (non-rodents)
- ruminant embryo production workshop + time-lapse
- epigenetic workshop: exploration of methylome in bovine, rabbit and mouse and with pipelines of bioinformatics and bio-statistical analyzes adapted
Keywords
Valuation offer
- testing the effect of pollutants or various molecules in these media on embryonic development and until birth
- development of imaging system non-invasive monitoring
Projects examples
- non-invasive gestation phenotyping by new ultrasonic medical imaging techniques
- morpho-kinetic biomark
Industrial and scientific relations
Scientific collaborations
Private collaborations
ALLICE (Federation of centers for insemination of bovine, ovine, caprine and procine species), Groupe Pilardière (animal food supplements), XR-Repro (animal insemination cooperatives), Xenothera (start-up developping innovative products in organ transplantation)
Establishments of affiliation
