• Quality of life - Health - Food

Biologie du Développement et Reproduction (BDR)

Research unit


UMR BDR research focuses on the mechanisms of phenotype development in farmed mammals.
The objective is to study the impact during embryonic and fetal development, culture medium, maternal nutrition, environmental pollutants, and livestock systems, on growth, health and the fertility of the offspring.
This work combines observations and measurements on cells, embryos, fetuses and animals at different ages. They aim at an understanding of the mechanisms involved, by imaging or molecular (epigenetic, metabolic and transcriptomic) analyzes. Research is carried out simultaneously on several species (mouse, rabbit, ruminants) allowing a comparative physiology approach. This work also uses reproductive biotechnologies used in animal husbandry.



Innovation themes

Map and access

INRA - Domaine de Vilvert - Bâtiment 230

Our research areas


- reproductive physiology
- developmental biology
- maternal-fetal interactions-placenta
- ovarian and testicular differentiation
-gametes formation
- epigenetics
- endocrinology
- pluripotency-stem cells
- genomes edition and epigenomas

Applications sectors

  • Biotechnology
  • Health / wellness

Total number of employees

Total number of employees : 94
Number of researchers : 26
Number of doctoral students : 11

Equipment(s) open to collaboration

Academics and industry:

Imaging platform (confocal and whole animal) MIMA2-BDR

- genetic modifications workshop in mammals (non-rodents)

- ruminant embryo production workshop + time-lapse

- epigenetic workshop: exploration of methylome in bovine, rabbit and mouse and with pipelines of bioinformatics and bio-statistical analyzes adapted


Our results

Valuation offer

- development and test of culture systems and media for mammalian embryos
- testing the effect of pollutants or various molecules in these media on embryonic development and until birth
- development of imaging system non-invasive monitoring

Projects examples

- development and evaluation of an early gestation test by measurement of interferon-dependent genes in circulating cells in ruminants

- non-invasive gestation phenotyping by new ultrasonic medical imaging techniques

- morpho-kinetic biomark

Industrial and scientific relations

Scientific collaborations


Private collaborations

ALLICE (Federation of centers for insemination of bovine, ovine, caprine and procine species), Groupe Pilardière (animal food supplements), XR-Repro (animal insemination cooperatives), Xenothera (start-up developping innovative products in organ transplantation)


Establishments of affiliation